Interoperability at Scale: A Conversation with Bryan Pellegrino

Listen in as our hosts are joined by Bryan Pellegrino, CEO and Co-founder of LayerZero Labs, to explore the evolving infrastructure powering blockchain interoperability.

From his unconventional journey—from poker pro to protocol architect—to the technical and economic implications of unified liquidity, Bryan shares his insights on tokenization, governance, and the future of agentic AI on-chain.

Whether you're crypto-native or crypto-curious, this episode offers a compelling look at how organizations like LayerZero are reshaping cross-chain communication and user experience.

Episode Topics:  

[0:00] Intro

[1:26] News Rundown

[2:55] Bryan’s Story

[4:58] An Introduction to Interoperability

[9:29] Innovations in Tokenization

[12:20] Governance Deep-dive

[17:01] Considerations for Unified Liquidity

[20:43] Facilitating Currency Exchange

[24:07] Exploring the Stargate Acquisition

[27:09] Opportunities for Agentic AI on-Chain

[30:22] Final Thoughts & Outro

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Please remember: this podcast is solely for informational and educational purposes and is not investment, tax, legal or insurance advice. Digital assets are speculative and highly volatile and you should conduct thorough research before you invest. To learn more, visit: fcatalyst.com FMR LLC. © 2025 FMR LLC. All rights reserved.